Most silicones are water-based products. They are used as fillers to fill gaps. Because they are mainly water based, they will not stick to a surface treated with MR Seal. The best way to do it, is to apply the silicone product first, then apply MR Seal sealants over the top. If you have already sealed the area with MR Seal, you will have to remove the sealer from the surface of the area first, before you can apply the silicone. First, you flush the area with turps. Then you flush the area with plenty of water and agitate with a scrubbing brush. Clean with a rag. Apply the silicone product to the cleaned surface and once the area is dry, you can then re-seal with MR Seal liquid product.